Experiment with Median Stacking
This is an experiment using high ISO source files and median stacking.
Compare the left-half of the photo against the right, and you will see a significant difference in noise.
Unfortunately, I only shot one frame, on the left-hand side and only had a large number of frames available to "median-stack", on the right-hand side. I want to reshoot this scene, next time the Great Reno Ballon Race returns.